A summary of the most common chemical descriptors (InChI Key and SMILES codes) for Azlocillin are summarized together with 3D and 2D structures and relevant physico-chemical properties.

What is the Azlocillin?

The molecule Azlocillin presents a molecular formula of C20H23N5O6S and its IUPAC name is (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.

Azlocillin is a penicillin antibiotic. It is used to treat certain types of bacterial infections. It will not work for viral infections (such as common cold, flu). Azlocillin belongs to a class of drugs called beta-lactam antibiotics. It works by stopping the growth of bacteria..

Azlocillin exists only with your doctor's prescription..

Before taking azlocillin,.

tell your doctor and pharmacist if you are allergic to azlocillin, penicillin, cephalosporins, or any other drugs..

tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins..

tell your doctor if you have or have ever had kidney disease or another medical condition..

you should know that azlocillin may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you..

remember that alcohol can add to the drowsiness caused by this medication..

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking azlocillin, call your doctor..

you should know that this medication may make you more likely to sunburn. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors..

if you have diabetes, you should know that this medication may make it harder to control your blood sugar. Check your blood sugar levels regularly as directed by your doctor..

Talk to your doctor about the risks and benefits of taking this medication..

3D structure

Cartesian coordinates

Geometry of Azlocillin in x, y and z coordinates (Å units) to copy/paste elsewhere. Generated with Open Babel software.

2D drawing


Azlocillin JTWOMNBEOCYFNV-NFFDBFGFSA-N chemical compound 2D structure molecule svg


Molecule descriptors

IUPAC name(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChI codeInChI=1S/C20H23N5O6S/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29)/t11-,12-,13+,16-/m1/s1

Other names (synonyms)

IUPAC nomenclature provides a standardized method for naming chemical compounds. Although this system is widely used in chemistry, many chemical compounds have also other names commonly used in different contexts. These synonyms can come from a variety of sources and are used for a variety of purposes.

One common source of synonyms for chemical compounds is the common or trivial names, assigned on the basis of appearance, properties, or origin of the molecule.

Another source of synonyms are historical or obsolete names employed in the past, however replaced nowadays by more modern or standardized names.

In addition to common and historical names, chemical compounds may also have synonyms that are specific to a particular field or industry.

  • (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-((R)-2-(2-oxo-1-imidazolidinecarboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
  • (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-((R)-2-(2-oxoimidazolidine-1-carboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetamido]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenyl-acetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2S)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenyl-acetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;Azlocillin
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 2,2-dimethyl-6beta-[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetamido]penam-3alpha-carboxylic acid
  • 37091-65-9
  • 37091-66-0
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(((((2-oxo-1-imidazolidinyl)carbonyl)amino)phenylacetyl)amino)-, (2S-(2alpha,5alpha,6beta(S*)))-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[[[((R)-2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-, (2S,5R,6R)-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-7-oxo-6-[[[[(2-oxo-1-imidazolidinyl)carbonyl]amino]phenylacetyl]amino]-, [2S-[2a,5a,6b(S*)]]-
  • 6-((R)-2-(2-Oxoimidazolidin-1-carboxamido)-2-phenylacetamido)penicillansaeure
  • 91A659
  • A823527
  • AC-8140
  • Azlocilina
  • Azlocillin
  • Azlocillin (USAN/INN)
  • Azlocillin sodium salt
  • Azlocilline
  • Azlocillinum
  • BPBio1_000817
  • BSPBio_000741
  • C06839
  • D02339
  • D81792
  • DB01061
  • DS-3291
  • Epitope ID:141185
  • HUM6H389W0
  • J01CA09
  • NSC 758227
  • NSC-758227
  • Prestwick3_000821
  • Q510154
  • azlocillin

Reference codes for other databases

There exist several different chemical codes commonly used in orded to identify molecules:
  • ZINC3830261
  • UNII-HUM6H389W0
  • AKOS025402328
  • BRD-K60663764-236-02-1
  • DTXSID1022639
  • CHEMBL1537
  • CHEBI:2956
  • EINECS 253-348-2
  • SCHEMBL34150

Physico-Chemical properties

IUPAC name(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Molecular formulaC20H23N5O6S
Molecular weight461.492
Melting point (ºC)
Boiling point (ºC)
Density (g/cm3)
Molar refractivity124.48
Topological polar surface area173.5

LogP and topological polar surface area (TPSA) values were estimated using Open Babel software.

The n-octanol/water partition coeficient (Kow) data is applied in toxicology and drug research. Kow values are used, to guess the environmental fate of persistent organic pollutants. High partition coefficients values, tend to accumulate in the fatty tissue of organisms. Molecules with a log(Kow) (or LogP) greater than 5 are considered to bioaccumulate.

TPSA values are the sum of the surface area over all polar atoms or molecules, mainly oxygen and nitrogen, also including hydrogen atoms.

In medicinal chemistry, TPSA is used to assess the ability of a drug to permeabilise cells.

For molecules to penetrate the blood-brain barrier (and act on receptors in the central nervous system), TPSA values below 90 Å2 are required. Thus, molecules with a polar surface area greater than 140 Å2 tend to be poorly permeable to cell membranes.