A summary of the most common chemical descriptors (InChI Key and SMILES codes) for 1H-Pyrrole are summarized together with 3D and 2D structures and relevant physico-chemical properties.

What is the 1H-Pyrrole?

The molecule 1H-Pyrrole presents a molecular formula of C4H5N and its IUPAC name is 1H-pyrrole.

Pyrrole is an aromatic organic compound with the chemical formula C4H4NH. It is a five-membered ring with four carbon atoms and one nitrogen atom. The nitrogen atom is not bonded to any hydrogen atoms. Pyrrole is a colourless liquid at room temperature and pressure, but it decomposes to give brown fumes above about 220 °C..

3D structure

Cartesian coordinates

Geometry of 1H-Pyrrole in x, y and z coordinates (Å units) to copy/paste elsewhere. Generated with Open Babel software.

2D drawing


1H-Pyrrole KAESVJOAVNADME-UHFFFAOYSA-N chemical compound 2D structure molecule svg


Molecule descriptors

IUPAC name1H-pyrrole
InChI codeInChI=1S/C4H5N/c1-2-4-5-3-1/h1-5H

Other names (synonyms)

IUPAC nomenclature provides a standardized method for naming chemical compounds. Although this system is widely used in chemistry, many chemical compounds have also other names commonly used in different contexts. These synonyms can come from a variety of sources and are used for a variety of purposes.

One common source of synonyms for chemical compounds is the common or trivial names, assigned on the basis of appearance, properties, or origin of the molecule.

Another source of synonyms are historical or obsolete names employed in the past, however replaced nowadays by more modern or standardized names.

In addition to common and historical names, chemical compounds may also have synonyms that are specific to a particular field or industry.

Reference codes for other databases

There exist several different chemical codes commonly used in orded to identify molecules:

Physico-Chemical properties

IUPAC name1H-pyrrole
Molecular formulaC4H5N
Molecular weight67.09
Melting point (ºC)-23
Boiling point (ºC)131
Density (g/cm3)0.967
Molar refractivity
Topological polar surface area15.8

LogP and topological polar surface area (TPSA) values were estimated using Open Babel software.

The n-octanol/water partition coeficient (Kow) data is applied in toxicology and drug research. Kow values are used, to guess the environmental fate of persistent organic pollutants. High partition coefficients values, tend to accumulate in the fatty tissue of organisms. Molecules with a log(Kow) (or LogP) greater than 5 are considered to bioaccumulate.

TPSA values are the sum of the surface area over all polar atoms or molecules, mainly oxygen and nitrogen, also including hydrogen atoms.

In medicinal chemistry, TPSA is used to assess the ability of a drug to permeabilise cells.

For molecules to penetrate the blood-brain barrier (and act on receptors in the central nervous system), TPSA values below 90 Å2 are required. Thus, molecules with a polar surface area greater than 140 Å2 tend to be poorly permeable to cell membranes.