L-Serine
A summary of the most common chemical descriptors (InChI Key and SMILES codes) for L-Serine are summarized together with 3D and 2D structures and relevant physico-chemical properties.
Table of Contents
What is the L-Serine?
The molecule L-Serine presents a molecular formula of C3H7NO3 and its IUPAC name is (2S)-2-amino-3-hydroxypropanoic acid.
L-Serine is an amino acid that is important for the proper functioning of the body. It is a non-essential amino acid, which means that it can be synthesized by the body and does not need to be obtained from the diet..
The L-serine molecule is composed of a carboxyl group, an amino group, and a hydrocarbon chain. It is involved in a number of important biochemical reactions in the body, including the synthesis of proteins, enzymes, and neurotransmitters..
L-Serine is essential for the synthesis of proteins, which are the building blocks of the body. It is also involved in the synthesis of enzymes, which are proteins that catalyze chemical reactions in the body, and neurotransmitters, which are chemicals that transmit signals between nerve cells..
L-Serine belongs in a variety of foods, including meat, poultry, fish, eggs, dairy products, and legumes. It can also be synthesized by the body from another amino acid called glycine..
Summary
From all the above, L-serine is an amino acid that is important for the proper functioning of the body. It is involved in the synthesis of proteins, enzymes, and neurotransmitters and belongs in a variety of foods. It can also be synthesized by the body from glycine..
3D structure
Cartesian coordinates
Geometry of L-Serine in x, y and z coordinates (Å units) to copy/paste elsewhere. Generated with Open Babel software.
2D drawing
Molecule descriptors
| IUPAC name | (2S)-2-amino-3-hydroxypropanoic acid |
| InChI code | InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1 |
| InChI Key | MTCFGRXMJLQNBG-REOHCLBHSA-N |
| SMILES | N[C@@H](CO)C(=O)O |
Other names (synonyms)
IUPAC nomenclature provides a standardized method for naming chemical compounds. Although this system is widely used in chemistry, many chemical compounds have also other names commonly used in different contexts. These synonyms can come from a variety of sources and are used for a variety of purposes.
One common source of synonyms for chemical compounds is the common or trivial names, assigned on the basis of appearance, properties, or origin of the molecule.
Another source of synonyms are historical or obsolete names employed in the past, however replaced nowadays by more modern or standardized names.
In addition to common and historical names, chemical compounds may also have synonyms that are specific to a particular field or industry.
- (-)-Serine
- (2S)-2-amino-3-hydroxy-propanoic acid
- (2S)-2-amino-3-hydroxypropanoic acid
- (2S)-2-amino-3-hydroxypropanoic acid.
- (L)-SERINE
- (S)-(+)-2-Amino-3-hydroxypropionic acid
- (S)-(-)-Serine
- (S)-2-Amino-3-hydroxypropanoate
- (S)-2-Amino-3-hydroxypropanoic acid
- (S)-2-Amino-3-hydroxypropionic acid
- (S)-2-amino-3-hydroxy-Propanoate
- (S)-2-amino-3-hydroxy-Propanoic acid
- (S)-Serine
- (S)-a-Amino-b-hydroxypropionate
- (S)-a-Amino-b-hydroxypropionic acid
- (S)-alpha-Amino-beta-hydroxypropionate
- (S)-alpha-Amino-beta-hydroxypropionic acid
- (S)-b-Amino-3-hydroxypropionate
- (S)-b-Amino-3-hydroxypropionic acid
- (S)-beta-Amino-3-hydroxypropionate
- (S)-beta-Amino-3-hydroxypropionic acid
- (s)-2-amino-3-hydroxypropanoicacid;2-Amion-3-hydroxypropionicacid
- .alpha.-Amino-.beta.-hydroxypropionic acid-, (S)-
- .beta.-Hydroxyalanine
- 064S224
- 2-Amino-3-hydroxypropanoic acid, (S)-
- 2-Amino-3-hydroxypropanoic acid-, (S)-
- 2-Amino-3-hydroxypropionic acid
- 2-amino-3-hydroxypropanoate
- 3-hydroxy-L-Alanine
- 3AB40D3A-043A-488F-8361-D1BF309F842C
- 3h-l-serine
- 452VLY9402
- 56-45-1
- 6898-95-9
- A20660
- AC-1190
- ACT08366
- AM20100375
- BDBM50357212
- BP-13282
- BRN 1721404
- C00065
- CCG-266038
- CS-W020136
- D00016
- DB-029983
- DB00133
- EC 200-274-3
- Epitope ID:150900
- F1905-7047
- Fmoc-(2-aminomethylphenyl)aceticacid
- GTPL726
- H-Ser
- H-Ser-OH
- HSDB 680
- HY-N0650
- L-(-)-Serine
- L-2-Amino-3-hydroxypropanoic Acid
- L-2-Amino-3-hydroxypropionic acid
- L-3-Hydroxy-2-aminopropionate
- L-3-Hydroxy-2-aminopropionic acid
- L-3-Hydroxy-alanine
- L-Alanine, 3-hydroxy-
- L-Serin
- L-Serine
- L-Serine (JP17)
- L-Serine - CAS 56-45-1
- L-Serine, tested according to Ph.Eur.
- L-Serine,(S)
- L-Serine;
- L-ser
- L-serine
- Lopac-S-4250
- MFCD00064224
- NCGC00015952-01
- NCGC00024507-01
- NCGC00024507-02
- NSC 118365
- NSC-118365
- NSC-760115
- NSC760115
- Pharmakon1600-01301010
- Propanoic acid, 2-amino-3-hydroxy-, (S)
- Propanoic acid, 2-amino-3-hydroxy-, (S)-
- Q183290
- Racemic serine
- S0035
- S9353
- SER (IUPAC abbrev)
- SR-01000597708
- SR-01000597708-1
- STR02557
- SY002847
- Serene
- Serina
- Serine (L-Serine)
- Serine, L-
- Serinum
- Tocris-0226
- Tocris-0227
- Z1270387256
- alpha-Amino-beta-hydroxypropionic acid
- b-Hydroxy-L-alanine
- beta-Hydroxy-L-alanine
- beta-Hydroxyalanine
- bmse000048
- bmse000809
- bmse000867
- bmse000885
- l-2-Amino-3-hydroxy-propanoic acid
- rac-serine
- ser
- serine
Reference codes for other databases
There exist several different chemical codes commonly used in orded to identify molecules:- CAS number (Chemical Abstracts Service Registry Number) is a unique identifier is assigned to every chemical compound indexed in the CAS database.
- Beilstein: The Beilstein database is a comprehensive source of information on organic chemistry, including information on chemical structures, properties, and reactions. The Beilstein database assigns unique identifiers which can be used to identify compounds in scientific literature and other sources.
- ChEBI (Chemical Entities of Biological Interest): ChEBI is a database of small chemical molecules that are of interest in the field of biology.
- PubChem CID (Compound Identifier): PubChem is a database of chemical compounds that is maintained by the National Institutes of Health (NIH).
- RTECS number (Registry of Toxic Effects of Chemical Substances): The RTECS is a database of information on the toxic effects of chemicals, including information on their structures and properties.
- ChEMBL (Compound Bioactivity Data): ChEMBL is a database of bioactivity data for small molecules, including information on their properties and structures.
- CompTox Dashboard (Environmental Protection Agency): The CompTox Dashboard is a database of information on the toxicology and environmental effects of chemicals.
- ZINC895034
- UNII-452VLY9402
- AKOS015854115
- DTXSID60883230
- DTXSID301031857
- CHEMBL11298
- CHEBI:17115
- EINECS 200-274-3
- SCHEMBL1775
Physico-Chemical properties
| IUPAC name | (2S)-2-amino-3-hydroxypropanoic acid |
| Molecular formula | C3H7NO3 |
| Molecular weight | 105.093 |
| Melting point (ºC) | |
| Boiling point (ºC) | |
| Density (g/cm3) | |
| Molar refractivity | 22.18 |
| LogP | -0.9 |
| Topological polar surface area | 83.6 |
LogP and topological polar surface area (TPSA) values were estimated using Open Babel software.
The n-octanol/water partition coeficient (Kow) data is applied in toxicology and drug research. Kow values are used, to guess the environmental fate of persistent organic pollutants. High partition coefficients values, tend to accumulate in the fatty tissue of organisms. Molecules with a log(Kow) (or LogP) greater than 5 are considered to bioaccumulate.
TPSA values are the sum of the surface area over all polar atoms or molecules, mainly oxygen and nitrogen, also including hydrogen atoms.
In medicinal chemistry, TPSA is used to assess the ability of a drug to permeabilise cells.
For molecules to penetrate the blood-brain barrier (and act on receptors in the central nervous system), TPSA values below 90 Å2 are required. Thus, molecules with a polar surface area greater than 140 Å2 tend to be poorly permeable to cell membranes.