Testosterone propionate

A summary of the most common chemical descriptors (InChI Key and SMILES codes) for Testosterone propionate are summarized together with 3D and 2D structures and relevant physico-chemical properties.

What is the Testosterone propionate?

The molecule Testosterone propionate presents a molecular formula of C22H32O3 and its IUPAC name is [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate.

Testosterone propionate is a synthetic androgen and anabolic steroid and a derivative of testosterone. It is specifically a prodrug of testosterone, and has strong androgenic and anabolic effects. Testosterone propionate is used in androgen replacement therapy, and has also been used to treat conditions such as male hypogonadism, androgen insensitivity syndrome, and delayed puberty..

Testosterone propionate is a white to off-white crystalline powder that is soluble in ethanol and slightly soluble in vegetable oils. It has a melting point of 87-89°C, and a boiling point of 196-198°C..

Testosterone propionate is a prodrug of testosterone, and has strong androgenic and anabolic effects. It is used in androgen replacement therapy, and has also been used to treat conditions such as male hypogonadism, androgen insensitivity syndrome, and delayed puberty. Testosterone propionate is also used in veterinary medicine, to promote muscle growth and appetite in animals..

Testosterone propionate has a half-life of approximately 2-3 days, and must be injected every other day or every third day to maintain stable serum testosterone levels..

3D structure

Cartesian coordinates

Geometry of Testosterone propionate in x, y and z coordinates (Å units) to copy/paste elsewhere. Generated with Open Babel software.

2D drawing


Testosterone propionate PDMMFKSKQVNJMI-BLQWBTBKSA-N chemical compound 2D structure molecule svg
Testosterone propionate


Molecule descriptors

IUPAC name[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate
InChI codeInChI=1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1

Other names (synonyms)

IUPAC nomenclature provides a standardized method for naming chemical compounds. Although this system is widely used in chemistry, many chemical compounds have also other names commonly used in different contexts. These synonyms can come from a variety of sources and are used for a variety of purposes.

One common source of synonyms for chemical compounds is the common or trivial names, assigned on the basis of appearance, properties, or origin of the molecule.

Another source of synonyms are historical or obsolete names employed in the past, however replaced nowadays by more modern or standardized names.

In addition to common and historical names, chemical compounds may also have synonyms that are specific to a particular field or industry.

  • (17beta)-3-oxoandrost-4-en-17-yl propanoate
  • (17beta)-3-oxoandrost-4-en-17-yl propionate
  • (1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate
  • .DELTA.4-androstene-17.beta.-propionate-3-one
  • 003T653
  • 17-(1-Oxopropoxy)androst-4-en-3-one, (17.beta.)-
  • 17-propionyl-17beta-hydroxyandrost-4-en-3-one
  • 17.beta.-(Propionyloxy)androst-4-en-3-one
  • 17.beta.-hydroxyandrost-4-en-3-one, propionate
  • 17beta-(Propionyloxy)androst-4-en-3-one
  • 17beta-Hydroxy-4-androsten-3-one 17-propionate
  • 17beta-Hydroxyandrost-4-en-3-one propionate
  • 17beta-Hydroxyandrost-4-en-3-one-17beta-propionate
  • 3-Oxoandrost-4-en-17-yl propionate, (17.beta.)-
  • 57-85-2
  • AC-12172
  • AC-33160
  • AI3-26378
  • Agovirin
  • Androgen
  • Androlon
  • Andronate
  • Androst-4-en-3-one, 17-(1-oxopropoxy)-(17.beta.)-
  • Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17.beta.)-
  • Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17b)-
  • Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17beta)-
  • Androst-4-en-3-one, 17.beta.-hydroxy-, propionate
  • Androst-4-en-3-one, 17beta-hydroxy-, propionate
  • Androsteston
  • Androtest P
  • Androteston
  • Andrusol-P
  • Aquaviron
  • BBL029912
  • BCP0726000215
  • BDBM50215709
  • BPBio1_000356
  • BSPBio_000322
  • Bio-testiculina
  • C08158
  • CCG-220401
  • CCRIS 575
  • CS-4905
  • D00959
  • DB01420
  • DSSTox_CID_16515
  • DSSTox_GSID_36515
  • DSSTox_RID_79286
  • Enarmon
  • Enarmon-oil
  • GTPL7100
  • HMS1569A04
  • HMS2096A04
  • HMS2272K06
  • HMS3713A04
  • HY-B1269
  • Homandren (amps)
  • Hormoteston
  • LMST02020076
  • MFCD00003653
  • MLS002153796
  • Masenate
  • NCGC00016254-01
  • NCGC00179602-01
  • NCGC00179602-03
  • NCGC00179602-06
  • NCGC00255481-01
  • NRB-03689
  • NSC 9166
  • NSC-9166
  • NSC9166
  • Nasdol
  • Neo-Hombreol
  • Okasa-Mascul
  • Orchiol
  • Orchisterone
  • Orchistin
  • Oreton propionate
  • Pantestin
  • Prestwick0_000401
  • Prestwick1_000401
  • Prestwick2_000401
  • Prestwick3_000401
  • Prestwick_432
  • Propiokan
  • Propionic acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester
  • Propionic acid 10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester
  • Propionic acid 10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester(Testosterone Propionate)
  • Q10354588
  • Recthormone testosterone
  • SMR000058348
  • STK801834
  • Solvotest
  • Sterandryl
  • Synandrol
  • Synerone
  • T0028
  • Telipex
  • Testaform
  • Testodet
  • Testodrin
  • Testogen
  • Testolets
  • Testonique
  • Testormol
  • Testosid
  • Testosteron 17-propionate
  • Testosteron propionate
  • Testosterone 17.beta.-propionate
  • Testosterone Propionate 1.0 mg/ml in Acetonitrile
  • Testosterone propionate
  • Testosterone propionate (Agovirin)
  • Testosterone propionate (JP17/USP)
  • Testosterone propionate ciii
  • Testosterone propionate, solid
  • Testosterone propionate, tested according to Ph.Eur.
  • Testosterone-17-beta-propionate
  • Testosterone-17-propionate
  • Testosterone-17.beta.-propionate
  • Testosterone-17.beta.propionate
  • Testosterone-17beta propionate
  • Testosterone-17beta-propionate
  • Testosteroni propionas
  • Testoviron (ampule)
  • Testoxyl
  • Testrex
  • Tostrin
  • Uniteston
  • VS-09499
  • Vulvan
  • W-105436
  • WI93Z9138A
  • WLN: L E5 B666 OV MUTJ A E FO52 -B&AEF
  • [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate
  • delta(sup 4)-Androstene-17-beta-propionate-3-one
  • testosteron-17-propionat
  • testosterone propionate

Reference codes for other databases

There exist several different chemical codes commonly used in orded to identify molecules:
  • ZINC490791
  • CAS-57-85-2
  • UNII-WI93Z9138A
  • AKOS005622513
  • AKOS015842719
  • BRD-K90553655-001-03-6
  • DTXSID9036515
  • CHEMBL1170
  • CHEBI:9466
  • Tox21_110330
  • Tox21_302270
  • Tox21_110330_1
  • EINECS 200-351-1
  • SPBio_002261
  • SCHEMBL4044

Physico-Chemical properties

IUPAC name[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate
Molecular formulaC22H32O3
Molecular weight344.488
Melting point (ºC)
Boiling point (ºC)
Density (g/cm3)
Molar refractivity99.90
Topological polar surface area43.4

LogP and topological polar surface area (TPSA) values were estimated using Open Babel software.

The n-octanol/water partition coeficient (Kow) data is applied in toxicology and drug research. Kow values are used, to guess the environmental fate of persistent organic pollutants. High partition coefficients values, tend to accumulate in the fatty tissue of organisms. Molecules with a log(Kow) (or LogP) greater than 5 are considered to bioaccumulate.

TPSA values are the sum of the surface area over all polar atoms or molecules, mainly oxygen and nitrogen, also including hydrogen atoms.

In medicinal chemistry, TPSA is used to assess the ability of a drug to permeabilise cells.

For molecules to penetrate the blood-brain barrier (and act on receptors in the central nervous system), TPSA values below 90 Å2 are required. Thus, molecules with a polar surface area greater than 140 Å2 tend to be poorly permeable to cell membranes.