(S)-4-aminohex-5-enoic acid

A summary of the most common chemical descriptors (InChI Key and SMILES codes) for (S)-4-aminohex-5-enoic acid are summarized together with 3D and 2D structures and relevant physico-chemical properties.

What is the (S)-4-aminohex-5-enoic acid?

The molecule (S)-4-aminohex-5-enoic acid presents a molecular formula of C6H11NO2 and its IUPAC name is (4S)-4-aminohex-5-enoic acid.

S-4-aminohex-5-enoic acid is an organic compound with the molecular formula C6H11NO2. It is a white solid that is soluble in water. It is a chiral molecule, meaning that it has two non-identical forms that are mirror images of each other. The two forms are called enantiomers..

3D structure

Cartesian coordinates

Geometry of (S)-4-aminohex-5-enoic acid in x, y and z coordinates (Å units) to copy/paste elsewhere. Generated with Open Babel software.

2D drawing

 

(S)-4-aminohex-5-enoic acid PJDFLNIOAUIZSL-RXMQYKEDSA-N chemical compound 2D structure molecule svg
(S)-4-aminohex-5-enoic acid

 

Molecule descriptors

 
IUPAC name(4S)-4-aminohex-5-enoic acid
InChI codeInChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m1/s1
InChI KeyPJDFLNIOAUIZSL-RXMQYKEDSA-N
SMILESC=C[C@@H](N)CCC(=O)O

Other names (synonyms)

IUPAC nomenclature provides a standardized method for naming chemical compounds. Although this system is widely used in chemistry, many chemical compounds have also other names commonly used in different contexts. These synonyms can come from a variety of sources and are used for a variety of purposes.

One common source of synonyms for chemical compounds is the common or trivial names, assigned on the basis of appearance, properties, or origin of the molecule.

Another source of synonyms are historical or obsolete names employed in the past, however replaced nowadays by more modern or standardized names.

In addition to common and historical names, chemical compounds may also have synonyms that are specific to a particular field or industry.

  • pound-VIGABATRIN
  • (+)-.GAMMA.-VINYL GABA
  • (+)-gamma-Vinyl GABA
  • (4S)-4-Amino-5-hexenoic Acid
  • (4S)-4-aminohex-5-enoic acid
  • (S)-(+)-Vigabatrin
  • (S)-4-Amino-5-hexenoic Acid
  • (S)-4-Aminohex-5-enic acid
  • (S)-4-aminohex-5-enoic acid
  • (S)-4-aminohex-5-enoicacid
  • (S)-Vigabatrin
  • 0S931RNJ68
  • 4(S)-Amino-5-hexenoic Acid
  • 5-Hexenoic acid, 4-amino-, (+)-
  • 5-Hexenoic acid, 4-amino-, (4S)-
  • 5-Hexenoic acid,4-amino-, (4S)-
  • 74046-07-4
  • A-Vigabatrin
  • A898147
  • BCP09861
  • MFCD00274076
  • Q27237189
  • RMI 71890
  • RMI-71890
  • S(+)-
  • S(+)--Vigabatrin
  • S(+)-4-Aminohexenoic acid
  • S(+)-gamma-Vigabatrin
  • S(+)-gamma-Vigabatrin, solid
  • S(+)-gamma-Vinyl GABA
  • S(+)-gamma-Vinyl-GABA
  • S-(+)-Vigabatrin
  • VIGABATRIN, S-(+)-
  • Vigabatrin, (S)-

Reference codes for other databases

There exist several different chemical codes commonly used in orded to identify molecules:
  • ZINC3798750
  • UNII-0S931RNJ68
  • AKOS006275524
  • DTXSID80224944
  • SCHEMBL465981

Physico-Chemical properties

IUPAC name(4S)-4-aminohex-5-enoic acid
Molecular formulaC6H11NO2
Molecular weight129.157
Melting point (ºC)
Boiling point (ºC)
Density (g/cm3)
Molar refractivity34.96
LogP1.1
Topological polar surface area63.3

LogP and topological polar surface area (TPSA) values were estimated using Open Babel software.

The n-octanol/water partition coeficient (Kow) data is applied in toxicology and drug research. Kow values are used, to guess the environmental fate of persistent organic pollutants. High partition coefficients values, tend to accumulate in the fatty tissue of organisms. Molecules with a log(Kow) (or LogP) greater than 5 are considered to bioaccumulate.

TPSA values are the sum of the surface area over all polar atoms or molecules, mainly oxygen and nitrogen, also including hydrogen atoms.

In medicinal chemistry, TPSA is used to assess the ability of a drug to permeabilise cells.

For molecules to penetrate the blood-brain barrier (and act on receptors in the central nervous system), TPSA values below 90 Å2 are required. Thus, molecules with a polar surface area greater than 140 Å2 tend to be poorly permeable to cell membranes.