A summary of the most common chemical descriptors (InChI Key and SMILES codes) for Pyritinol are summarized together with 3D and 2D structures and relevant physico-chemical properties.

What is the Pyritinol?

The molecule Pyritinol presents a molecular formula of C16H20N2O4S2 and its IUPAC name is 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol.

Pyritinol is a nootropic drug that has been shown to improve cognitive function in a variety of studies. It is thought to work by increasing levels of acetylcholine and dopamine in the brain. Pyritinol has also been shown to protect the brain from damage caused by alcohol and other toxins..

3D structure

Cartesian coordinates

Geometry of Pyritinol in x, y and z coordinates (Å units) to copy/paste elsewhere. Generated with Open Babel software.

2D drawing


Pyritinol SIXLXDIJGIWWFU-UHFFFAOYSA-N chemical compound 2D structure molecule svg


Molecule descriptors

IUPAC name5-[[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol
InChI codeInChI=1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3

Other names (synonyms)

IUPAC nomenclature provides a standardized method for naming chemical compounds. Although this system is widely used in chemistry, many chemical compounds have also other names commonly used in different contexts. These synonyms can come from a variety of sources and are used for a variety of purposes.

One common source of synonyms for chemical compounds is the common or trivial names, assigned on the basis of appearance, properties, or origin of the molecule.

Another source of synonyms are historical or obsolete names employed in the past, however replaced nowadays by more modern or standardized names.

In addition to common and historical names, chemical compounds may also have synonyms that are specific to a particular field or industry.

  • 1098-97-1
  • 3,3'-(Dithiobis(methylene))bis(5-hydroxy-6-methyl-4-pyridinemethanol)
  • 3,3'-(Dithiodimethylene)bis(5-hydroxy-6-methyl-4-pyridinemethanol)
  • 4-(hydroxymethyl)-5-[[[4-(hydroxymethyl)-6-methyl-5-oxidanyl-pyridin-3-yl]methyldisulfanyl]methyl]-2-methyl-pyridin-3-ol
  • 4-Pyridinemethanol, 3,3'-(dithiobis(methylene))bis(5-hydroxy-6-methyl-
  • 4-Pyridinemethanol, 3,3'-(dithiodimethylene)bis(5-hydroxy-6-methyl-
  • 5,5'-(Disulfanediylbis(methylene))bis(4-(hydroxymethyl)-2-methylpyridin-3-ol)
  • 5,5'-(disulfanediyldimethanediyl)bis[4-(hydroxymethyl)-2-methylpyridin-3-ol]
  • 5,5'-(dithiodimethylene) bis[3-hydroxy-4-hydroxymethyl-2-methylpyridine]
  • 5,5'-(dithiodimethylene)bis[3-hydroxy-4-hydroxymethyl-2-methylpyridine]
  • 5,5'-Disulfanediylbis(methylene)bis(4-(hydroxymethyl)-2-methylpyridin-3-ol)
  • 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridinyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-3-pyridinol
  • 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridyl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methyl-pyridin-3-ol
  • 5-[[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol
  • A802103
  • AB00375835_02
  • AC-12193
  • AK5Q5FZH2R
  • AS-13595
  • BBL028281
  • Biocefalin
  • Bis(4-hydroxymethyl-5-hydroxy-6-methyl-3-pyridylmethyl)disulfide
  • Bonifen
  • Bonol
  • C71346
  • CCG-213980
  • D02160
  • DB-050233
  • DB13084
  • Dipyridoxolyldisulfide
  • Encefabol
  • Epocan
  • FT-0674240
  • HMS3264M15
  • HMS3886M13
  • HY-B0910
  • MFCD00151477
  • MLS004712044
  • NCGC00166140-01
  • NSC 759229
  • NSC-759229
  • NSC759229
  • P2250
  • PYRITINOL, Pyrithioxin
  • Pharmakon1600-01505762
  • Piritinol
  • Piritinolo
  • Pyridoxine disulfide
  • Pyridoxine-5-disulfide
  • Pyrithioxin
  • Pyrithioxine
  • Pyrithioxine (JAN)
  • Pyrithioxine hydrochloride
  • Pyritinol
  • Pyritinol (INN)
  • Pyritinolum
  • Pyritioxine
  • Q416361
  • SBI-0207045.P001
  • SMR001550535
  • SR-01000872772
  • SR-01000872772-1
  • STK801801
  • Vitamin B6 disulfide
  • W-108702
  • s5141

Reference codes for other databases

There exist several different chemical codes commonly used in orded to identify molecules:
  • ZINC37866091
  • AKOS005066380
  • BRD-K82181219-001-01-9
  • DTXSID3048362
  • CHEMBL488093
  • CHEBI:135554
  • EINECS 214-150-1
  • SCHEMBL150551

Physico-Chemical properties

IUPAC name5-[[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methyldisulfanyl]methyl]-4-(hydroxymethyl)-2-methylpyridin-3-ol
Molecular formulaC16H20N2O4S2
Molecular weight368.471
Melting point (ºC)
Boiling point (ºC)
Density (g/cm3)
Molar refractivity97.71
Topological polar surface area157.3

LogP and topological polar surface area (TPSA) values were estimated using Open Babel software.

The n-octanol/water partition coeficient (Kow) data is applied in toxicology and drug research. Kow values are used, to guess the environmental fate of persistent organic pollutants. High partition coefficients values, tend to accumulate in the fatty tissue of organisms. Molecules with a log(Kow) (or LogP) greater than 5 are considered to bioaccumulate.

TPSA values are the sum of the surface area over all polar atoms or molecules, mainly oxygen and nitrogen, also including hydrogen atoms.

In medicinal chemistry, TPSA is used to assess the ability of a drug to permeabilise cells.

For molecules to penetrate the blood-brain barrier (and act on receptors in the central nervous system), TPSA values below 90 Å2 are required. Thus, molecules with a polar surface area greater than 140 Å2 tend to be poorly permeable to cell membranes.