(2R)-2-aminopropionic acid benzyl ester

A summary of the most common chemical descriptors (InChI Key and SMILES codes) for (2R)-2-aminopropionic acid benzyl ester are summarized together with 3D and 2D structures and relevant physico-chemical properties.

What is (2R)-2-aminopropionic acid benzyl ester?

The molecule (2R)-2-aminopropionic acid benzyl ester presents a molecular formula of C10H13NO2 and its IUPAC name is (phenylmethyl) (2R)-2-azanylpropanoate.

3D structure

Cartesian coordinates

Geometry of (2R)-2-aminopropionic acid benzyl ester in x, y and z coordinates (Å units) to copy/paste elsewhere. Generated with Open Babel software.

2D drawing


(2R)-2-aminopropionic acid benzyl ester YGYLYUIRSJSFJS-MRVPVSSYSA-N chemical compound 2D structure molecule svg
(2R)-2-aminopropionic acid benzyl ester


Molecule descriptors

IUPAC name(2R)-2-aminopropionic acid benzyl ester
InChI codeInChI=1S/C10H13NO2/c1-8(11)10(12)13-7-9-5-3-2-4-6-9/h2-6,8H,7,11H2,1H3/t8-/m1/s1

Physico-Chemical properties

IUPAC name(phenylmethyl) (2R)-2-azanylpropanoate
Molecular formulaC10H13NO2
Molecular weight179.22
Melting point (ºC)
Boiling point (ºC)
Density (g/cm3)
Molar refractivity
Topological polar surface area52.3

LogP and topological polar surface area (TPSA) values were estimated using Open Babel software.

The n-octanol/water partition coeficient (Kow) data is applied in toxicology and drug research. Kow values are used, to guess the environmental fate of persistent organic pollutants. High partition coefficients values, tend to accumulate in the fatty tissue of organisms. Molecules with a log(Kow) (or LogP) greater than 5 are considered to bioaccumulate.

TPSA values are the sum of the surface area over all polar atoms or molecules, mainly oxygen and nitrogen, also including hydrogen atoms.

In medicinal chemistry, TPSA is used to assess the ability of a drug to permeabilise cells.

For molecules to penetrate the blood-brain barrier (and act on receptors in the central nervous system), TPSA values below 90 Å2 are required. Thus, molecules with a polar surface area greater than 140 Å2 tend to be poorly permeable to cell membranes.